Potential of E-Learning Interventions and Artificial Intelligence-Assisted Contouring Skills in Radiotherapy: The ELAISA Study.
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Rasmussen Mathis Ersted, Akbarov Kamal, Titovich Egor, Nijkamp Jasper Albertus, Van Elmpt Wouter, Primdahl Hanne, Lassen Pernille, Cacicedo Jon, Cordero-Mendez Lisbeth, Uddin A F M Kamal, Mohamed Ahmed, Prajogi Ben, Brohet Kartika Erida, Nyongesa Catherine, Lomidze Darejan, Prasiko Gisupnikha, Ferraris Gustavo, Mahmood Humera, Stojkovski Igor, Isayev Isa, Mohamad Issa, Shirley Leivon, Kochbati Lotfi, Eftodiev Ludmila, Piatkevich Maksim, Bonilla Jara Maria Matilde, Spahiu Orges, Aralbayev Rakhat, Zakirova Raushan, Subramaniam Sandya, Kibudde Solomon, Tsegmed Uranchimeg, Korreman Stine Sofia, Eriksen Jesper Grau
Аннотация
MATERIALS AND METHODS: Ninety-seven ROs were randomly assigned to either manual or AI-assisted contouring of eight OARs for two head-and-neck cancer cases with an in-between teaching session on contouring guidelines. Thereby, the effect of teaching (yes/no) and AI-assisted contouring (yes/no) was quantified. Second, ROs completed short-term and long-term follow-up cases all using AI assistance. Contour quality was quantified with Dice Similarity Coefficient (DSC) between ROs' contours and expert consensus contours. Groups were compared using absolute differences in medians with 95% CIs.
RESULTS: AI-assisted contouring without previous teaching increased absolute DSC for optic nerve (by 0.05 [0.01; 0.10]), oral cavity (0.10 [0.06; 0.13]), parotid (0.07 [0.05; 0.12]), spinal cord (0.04 [0.01; 0.06]), and mandible (0.02 [0.01; 0.03]). Contouring time decreased for brain stem (-1.41 [-2.44; -0.25]), mandible (-6.60 [-8.09; -3.35]), optic nerve (-0.19 [-0.47; -0.02]), parotid (-1.80 [-2.66; -0.32]), and thyroid (-1.03 [-2.18; -0.05]). Without AI-assisted contouring, teaching increased DSC for oral cavity (0.05 [0.01; 0.09]) and thyroid (0.04 [0.02; 0.07]), and contouring time increased for mandible (2.36 [-0.51; 5.14]), oral cavity (1.42 [-0.08; 4.14]), and thyroid (1.60 [-0.04; 2.22]).
CONCLUSION: The study suggested that AI-assisted contouring is safe and beneficial to ROs working in LMICs. Prospective clinical trials on AI-assisted contouring should, however, be conducted upon clinical implementation to confirm the effects.