Diagnosis Algorithm of Cardiac Sarcoidosis: Where Are We?

This commentary discusses the recently published article, "Speckle-tracking echocardiography as an effective screening tool for cardiac involvement among patients with systemic sarcoidosis in an Indian cohort: A prospective observational study". Owing to improved imaging modalities and increased awareness of cardiac sarcoidosis (CS), the prevalence of CS has risen. Given that CS is a relatively rare condition with high mortality, it is essential for the initial test to demonstrate high sensitivity. However, several guidelines offer differing opinions on the diagnosis algorithm for CS. This commentary highlighted the importance of speckle-tracking echocardiography as an effective screening tool. Due to its high negative predictive value (NPV), it would be useful to rule out cardiac involvement. Nevertheless, larger prospective multicenter studies are warranted to develop a more cost-effective diagnosis algorithm for CS.