The journal of allergy and clinical immunology. In practice · 2020
Clinical Practice of Allergen Immunotherapy for Allergic Rhinoconjunctivitis and Asthma: An Expert Panel Report.
СтатьяПоддержка исследования: вне правительства СШАОбзорНазвание и аннотация: Перевод пока не подготовлен
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Calderon Moisés A, Waserman Susan, Bernstein David I, Demoly Pascal, Douglass Jo, Gagnon Remi, Katelaris Constance H, Kim Harold, Nelson Harold S, Okamoto Yoshitaka, Okubo Kimihiro, Virchow J Christian, DuBuske Lawrence, Casale Thomas B, Canonica G Walter, Nolte Hendrik
Аннотация
Allergen immunotherapy (AIT) reduces symptoms and medication use associated with allergic rhinitis with or without conjunctivitis and allergic asthma. Although several AIT guidelines exist, there remain unanswered questions about AIT that are relevant to everyday practice. Our objective was to prepare an evidence-based overview addressing the practical aspects of AIT in clinical practice based on published evidence and the experience of international experts in the field. Topics covered include interpretation and translation of clinical trial data into everyday clinical practice (eg, allergen doses and treatment duration), assessment of risk and treatment of local and systemic allergic reactions, recommendations for improvement of AIT guidelines, and identification of appropriate data for seeking regulatory approval, to name a few. Many informational gaps in AIT practice need further evaluation as products and practices evolve.