[Effects of milk with inulin and vitamin D_3 on bone health and gastrointestine symptoms in lactose intolerance population].

OBJECTIVE

To investigate the effects of milk with inulin and vitamin D3 on bone health and gastrointestinal symptoms in lactose intolerance( LI) population.

METHODS

A total of 42 volunteers diagnosed as LI by breath hydrogen test were randomized into A or B group. Whole milk supplemented with inulin( 150 mg /100 g), vitamin D3( 2. 0μg /100 g), casein phosphopeptides( 5. 0 mg /100 m L), milk minerals( 40 mg /100 g), and low-lactose whole milk were given to A or B groups respectively. Bone mass density( BMD), calcium absorption and gastrointestinal symptoms were measured at the 0th and6 th week of the intervention.

RESULTS

After 6 weeks, BMD increased significantly in group A( P = 0. 013). In group B, BMD also increased but the trend was not significant. Calcium absorption increased in group A but decreased slightly in group B, the trends in both groups lacked of statistic significant. Gastrointestinal symptoms were ameliorated in both groups, but still there was no significance. For all the measurements, there was nostatistic significant difference between groups.

CONCLUSION

Milk with inulin and vitamin D3 could improve bone health in LI population, gastrointestinal symptoms after drinking this certain milk were analogous to low lactose milk.