DOI 10.1097/ico.0000000000001183
Endocan Overexpression in Pterygium.
Аннотация
PURPOSE: The aim of this study was to evaluate the possible role of endocan in the pathogenesis of pterygium.
METHODS
The study was conducted on 33 patients with primary pterygium and 20 control subjects with normal bulbar conjunctiva. Patients with pterygium were graded into 3 groups as atrophic, fleshy, and intermediate, according to the Tan classification. Primary nasal pterygia and normal bulbar conjunctivas were surgically removed. Endocan expression was immunohistochemically investigated.
RESULTS
Endocan expression in epithelial and endothelial cells was statistically significantly higher in pterygium tissues than control tissues (P = 0.001). No significant correlation was observed between pterygium classification groups and endocan expression in both epithelial and endothelial cells (P > 0.05).
CONCLUSIONS
The results suggest that endocan may have a role in the pathogenesis of pterygium.
Предметные рубрики MeSH
Подготовка и перевод публикации
Обработка статьи · этапы, ошибки и управление
Ошибки и ограничения
История · было → стало
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