Evaluation of a New Fully Automatic OLCR Biometer: Repeatability, Reproducibility, and Agreement with an SS-OCT Biometer.

INTRODUCTION

This study aimed to evaluate the intraobserver repeatability and interobserver reproducibility of the LUS-1000 Plus, a new fully automatic optical low coherence reflectometry (OLCR)-based biometer, and its agreement with the IOLMaster 700, a swept-source optical coherence tomography (SS-OCT)-based biometer, for biometric measurement.

METHODS

This prospective study included 77 right eyes from 77 healthy participants. The axial length (AL), central corneal thickness (CCT), aqueous depth (AQD), anterior chamber depth (ACD), flattest, steepest, mean keratometry (Kf, Ks, Km), astigmatism magnitude (AST), J0, J45 vectors, and corneal diameter (CD) were measured. Repeatability and reproducibility were evaluated using the within-subject standard deviation (Sw), test-retest (TRT) repeatability, coefficient of variation (CoV), and intraclass correlation coefficient (ICC). To compare differences and establish agreement between the devices, paired t test and Bland-Altman plots were utilized. Double-angle plots were employed to analyze corneal astigmatism.

RESULTS

Repeatability and reproducibility analysis revealed low Sw, TRT, and CoV, accompanied by high ICC values for all evaluated parameters. The interdevice agreement was excellent, Bland-Altman plots showed narrow 95% limits of agreement (LoA) (AL - 0.05 to 0.04 mm, CCT - 22.03 to - 7.50 μm, AQD 0.01 to 0.14 mm, ACD 0.00 to 0.13 mm, LT - 0.16 to 0.02 mm, Kf - 0.24 to 0.23 D, Ks - 0.36 to 0.21 D, Km - 0.24 to 0.16 D, AST - 0.41 to 0.27 D, J0 - 0.15 to 0.17 D, J45 - 0.14 to 0.22 D, CD - 0.38 to 0.18 mm).

CONCLUSION

The LUS-1000 Plus demonstrated high repeatability and reproducibility, and excellent agreement with the IOLMaster 700, confirming its reliability and interchangeable use with the IOLMaster 700 in clinical practice.