European journal of ophthalmology · 2020
Intravitreal bevacizumab in cystoid macular edema associated to maternally inherited diabetes and deafness's macular dystrophy.
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Marco-Campmany Amelia, Pacheco-Cervera Jana, Navarrete-Sanchis Javier, Tomás-Torrent Juan Miguel, García-Canet Sara, Cuadrado-Gómez Teresa
Аннотация
INTRODUCTION: Maternally inherited diabetes and deafness (MIDD) is a rare and infradiagnosed cause of diabetes which can, in a high number of cases, associate a macular dystrophy.
CASE PRESENTATION: We report the case of a 49- year-old man affected of this syndrome, with proven m3243G>A mitochondrial mutation, who developed macular cysts 20 years after the initial presentation of his macular dystrophy. The fluorescein angiography showed no leakage, ruling out a diabetic macular edema. A treatment with intravitreal bevacizumab led to cystic changes resolution and visual acuity recovery.
CONCLUSION: Intravitreal bevacizumab can be successfully employed for this complication of MIDD's macular dystrophy.
CASE PRESENTATION: We report the case of a 49- year-old man affected of this syndrome, with proven m3243G>A mitochondrial mutation, who developed macular cysts 20 years after the initial presentation of his macular dystrophy. The fluorescein angiography showed no leakage, ruling out a diabetic macular edema. A treatment with intravitreal bevacizumab led to cystic changes resolution and visual acuity recovery.
CONCLUSION: Intravitreal bevacizumab can be successfully employed for this complication of MIDD's macular dystrophy.