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DOI 10.1016/j.bjorl.2014.12.010

Медицинская библиотека · Brazilian journal of otorhinolaryngology · 2015

Cancer treatment in determination of hearing loss.

Oliveira Priscila Feliciano de, Oliveira Camila Silva, Andrade Joice Santos, Santos Tamara Figueiredo do Carmo, Oliveira-Barreto Aline Cabral de

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Аннотация

INTRODUCTION

Chemotherapy and radiotherapy in oncology have repercussions in hearing health, and can damage structures of the inner ear. These repercussions usually, result in a bilateral and irreversible hearing loss.

OBJECTIVE

To identify sensorineural hearing loss cases with complaints of tinnitus and difficulty in speech understanding and investigate their relationship with the types of chemotherapy and radiotherapy the patients received.

METHODS

Cross-sectional, clinical, observational, analytical, historical cohort study of 58 subjects treated in a public hospital in the state of Sergipe, diagnosed with neoplasia. The subjects were submitted to anamnesis, conventional pure tone audiometry, and speech recognition threshold.

RESULTS

Of the 116 ears, 25.9% presented sensorioneural hearing loss characterized by changes in high frequencies. There was a positive correlation between hearing loss and the association of chemotherapy and radiotherapy (p=0.035; R=0.196). The auditory complaint analysis shows that most of the subjects had tinnitus and speech understanding difficulty, even with a normal auditory threshold.

CONCLUSIONS

Cancer treatment causes hearing loss, associated with the administration of chemotherapy and radiotherapy. Cyclophosphamide increased the risk of causing hearing loss. Complaints of tinnitus and speech understanding difficulty were observed.

Для цитирования: Oliveira Priscila Feliciano de, Oliveira Camila Silva, Andrade Joice Santos, Santos Tamara Figueiredo do Carmo, Oliveira-Barreto Aline Cabral de. Cancer treatment in determination of hearing loss.. Brazilian journal of otorhinolaryngology. 2015. DOI: 10.1016/j.bjorl.2014.12.010.

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