Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology · 2001
Acoustic neuromas in the elderly.
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Perry B P, Gantz B J, Rubinstein J T
Аннотация
OBJECTIVE: To determine if an "observation" protocol with serial scanning is a safe and effective management paradigm for acoustic neuromas in the elderly.
STUDY DESIGN: A retrospective case review was performed.
SETTING: This study was performed in an academic, tertiary care center.
PATIENTS: Forty-one patients over the age of 65 years were identified with the primary diagnosis of unilateral acoustic neuroma, without prior treatment or observation.
INTERVENTION: The patients were followed with serial, gadolinium-enhanced magnetic resonance imaging (MRI) scans performed at 6 months and then yearly, if no significant growth occurred.
MAIN OUTCOME MEASURES: The patients were monitored for tumor growth, cranial nerve deficits, and hydrocephalus.
RESULTS: The patients were followed for an average of 3.5 years (range, 6 months to 9 years). The average tumor size at presentation was 1.14 cm, with a range of growth rates from 0 to 1.2 cm per year. Twenty-one patients demonstrated tumor growth at an average rate of 0.322 cm per year. Only five patients (12%) required further intervention. Three patients underwent translabyrinthine excision, and two patients were treated with radiation. No patients developed significant complications during the observation period.
CONCLUSIONS: Acoustic neuromas in the older population can be managed safely using serial MRI scanning. No correlation could be made between initial tumor size and subsequent growth rate.
STUDY DESIGN: A retrospective case review was performed.
SETTING: This study was performed in an academic, tertiary care center.
PATIENTS: Forty-one patients over the age of 65 years were identified with the primary diagnosis of unilateral acoustic neuroma, without prior treatment or observation.
INTERVENTION: The patients were followed with serial, gadolinium-enhanced magnetic resonance imaging (MRI) scans performed at 6 months and then yearly, if no significant growth occurred.
MAIN OUTCOME MEASURES: The patients were monitored for tumor growth, cranial nerve deficits, and hydrocephalus.
RESULTS: The patients were followed for an average of 3.5 years (range, 6 months to 9 years). The average tumor size at presentation was 1.14 cm, with a range of growth rates from 0 to 1.2 cm per year. Twenty-one patients demonstrated tumor growth at an average rate of 0.322 cm per year. Only five patients (12%) required further intervention. Three patients underwent translabyrinthine excision, and two patients were treated with radiation. No patients developed significant complications during the observation period.
CONCLUSIONS: Acoustic neuromas in the older population can be managed safely using serial MRI scanning. No correlation could be made between initial tumor size and subsequent growth rate.