Ahaptoglobinemia in Favism patients from Iran.

Haptoglobin patterns were studied in Favism patients (n = 361). G6PD deficients (n = 42) and healthy controls (n = 168). A high frequency of ahaptoglobinemia (79.50%) was found in Favism patients. No such type was detected in the G6PD deficients and the control group. In the Favism patients, the Hp2-1 and Hp2-2 patterns exhibited the normal and weak (Hypo) type, whereas the G6PD deficient and normal samples did not show such a differentiation. The Hp2 allele frequency was noted to be slightly higher in the G6PD deficient persons.