Diabetes research and clinical practice · 2026
Cardiometabolic multimorbidity prevalence and mortality risks in Chinese old-old population: real-world evidence from continuing care retirement community.
СтатьяНаблюдательное исследованиеНазвание и аннотация: Перевод пока не подготовлен
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Cao Yunfeng, Wang Zixuan, Wang Fan, Fu Yan, Fan Jin, Zhang Chunfang, Li Ming, Zheng Binli, Zi Jie, Yu Xinxiu, Huang Jiajia, Tang Lu, Yu Peng, Wu Rong, Chang Cheng, Wang Zhong, Yin Jiabao, Yang Wenying
Аннотация
AIMS: To provide evidence on cardiometabolic multimorbidity (CMM) among very elderly Chinese.
METHODS: This was a retrospective analysis of Chinese elderly in Taikang Community. Cardiometabolic disease [hypertension, diabetes, coronary artery disease (CHD), stroke, and heart failure (HF)] prevalence and CMM patterns were presented. A subgroup with follow-up records was further evaluated for the disease management outcomes. The mortality risks of various diseases were assessed using weighted logistic regression.
RESULTS: A total of 20,360 older adults (median age 83.3 years) were included. Hypertension (78.8%) was the most prevalent cardiometabolic condition. The overall CMM prevalence was 51.8%, with hypertension-diabetes being the most prevalent pattern (16.5%). During follow-up, the achievement rates for hypertension, diabetes, and CHD management were 54.6%, 70.0%, and 18.1%, respectively. The independent mortality risk of the diseases was HF, CHD, stroke, diabetes, and hypertension in descending order. Diabetes as a comorbidity of hypertension had minimal influence on the mortality risk.
CONCLUSIONS: Among Chinese old-old population, hypertension was the most prevalent cardiometabolic condition, with hypertension-diabetes being the most prevalent CMM pattern. Uncomplicated hypertension or diabetes without organ damage was associated with limited increase in mortality risk when well-managed, whereas HF as the greatest risk factor warrant more proactive follow-up interventions.
METHODS: This was a retrospective analysis of Chinese elderly in Taikang Community. Cardiometabolic disease [hypertension, diabetes, coronary artery disease (CHD), stroke, and heart failure (HF)] prevalence and CMM patterns were presented. A subgroup with follow-up records was further evaluated for the disease management outcomes. The mortality risks of various diseases were assessed using weighted logistic regression.
RESULTS: A total of 20,360 older adults (median age 83.3 years) were included. Hypertension (78.8%) was the most prevalent cardiometabolic condition. The overall CMM prevalence was 51.8%, with hypertension-diabetes being the most prevalent pattern (16.5%). During follow-up, the achievement rates for hypertension, diabetes, and CHD management were 54.6%, 70.0%, and 18.1%, respectively. The independent mortality risk of the diseases was HF, CHD, stroke, diabetes, and hypertension in descending order. Diabetes as a comorbidity of hypertension had minimal influence on the mortality risk.
CONCLUSIONS: Among Chinese old-old population, hypertension was the most prevalent cardiometabolic condition, with hypertension-diabetes being the most prevalent CMM pattern. Uncomplicated hypertension or diabetes without organ damage was associated with limited increase in mortality risk when well-managed, whereas HF as the greatest risk factor warrant more proactive follow-up interventions.