Otolaryngologia polska = The Polish otolaryngology · 2006
[The role of helicobacter pylori infection in carcinoma of the larynx].
СтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Burduk Paweł K
Аннотация
INTRODUCTION: Helicobacter pylori causes different chronic infections that has been linked to the development of malignant disease of the aerodigestive tract. The larynx as a part of upper aerodigestive tract could be infected with this bacteria, mostly by gastroesophageal reflux.
MATERIAL AND METHODS: In our study rapid urease tests were performed on the tissue samples of 80 patients with laryngeal squamous cell carcinoma and 34 control with benign laryngeal pathology.
RESULTS: In the evaluation of 80 specimens with laryngeal cancer in 62.5% we recorded a positive urease test reaction pointing for coexisting Helicobacter pylori infection and in 37.8% of cases the negative reaction. In the control group a positive reaction was in 47.3% of cases and negative in 52.7% of cases.
CONCLUSIONS: Inflammation inducted by Helicobacter pylori would cause epithelial cell proliferation and could follow to development of laryngeal cancer. Thus, laryngeal tissue can be colonized by some other agents containing a urease enzyme other than Helicobacter pylori an additional tests may be performed. In our future investigation we are trying to estimate the Helicobacter pylori infection in pathologic tissue using a polymerase chain reaction (PCR).
MATERIAL AND METHODS: In our study rapid urease tests were performed on the tissue samples of 80 patients with laryngeal squamous cell carcinoma and 34 control with benign laryngeal pathology.
RESULTS: In the evaluation of 80 specimens with laryngeal cancer in 62.5% we recorded a positive urease test reaction pointing for coexisting Helicobacter pylori infection and in 37.8% of cases the negative reaction. In the control group a positive reaction was in 47.3% of cases and negative in 52.7% of cases.
CONCLUSIONS: Inflammation inducted by Helicobacter pylori would cause epithelial cell proliferation and could follow to development of laryngeal cancer. Thus, laryngeal tissue can be colonized by some other agents containing a urease enzyme other than Helicobacter pylori an additional tests may be performed. In our future investigation we are trying to estimate the Helicobacter pylori infection in pathologic tissue using a polymerase chain reaction (PCR).