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DOI 10.1038/nrd4696

Медицинская библиотека · Nature reviews. Drug discovery · 2015

Towards host-directed therapies for tuberculosis.

Zumla Alimuddin, Maeurer Markus, Host-Directed Therapies Network, Chakaya Jeremiah, Hoelscher Michael, Ntoumi Francine, Rustomjee Roxana, Vilaplana Cristina, Yeboah-Manu Dorothy, Rasolof Voahangy, Munderi Paula, Singh Nalini, Aklillu Eleni, Padayatchi Nesri, Macete Eusebio, Kapata Nathan, Mulenga Modest, Kibiki Gibson, Mfinanga Sayoki, Nyirenda Thomas, Maboko Leonard, Garcia-Basteiro Alberto, Rakotosamimanana Niaina, Bates Matthew, Mwaba Peter, Reither Klaus, Gagneux Sebastien, Edwards Sarah, Mfinanga Elirehema, Abdulla Salim, Cardona Pere-Joan, Russell James B W, Gant Vanya, Noursadeghi Mahdad, Elkington Paul, Bonnet Maryline, Menendez Clara, Dieye Tandakha N, Diarra Bassirou, Maiga Almoustapha, Aseffa Abraham, Parida Shreemanta, Wejse Christian, Petersen Eskild, Kaleebu Pontiano, Oliver Matt, Craig Gill, Corrah Tumena, Tientcheu Leopold, Antonio Martin, Rao Martin, McHugh Timothy D, Sheikh Aziz, Ippolito Giuseppe, Ramjee Gita, Kaufmann Stefan H E, Churchyard Gavin, Steyn Andrie, Grobusch Martin, Sanne Ian, Martinson Neil, Madansein Rajhmun, Wilkinson Robert J, Mayosi Bongani, Schito Marco, Wallis Robert S

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Аннотация

The treatment of tuberculosis is based on combinations of drugs that directly target Mycobacterium tuberculosis. A new global initiative is now focusing on a complementary approach of developing adjunct host-directed therapies.

Для цитирования: Zumla Alimuddin, Maeurer Markus, Host-Directed Therapies Network, Chakaya Jeremiah, Hoelscher Michael, Ntoumi Francine, Rustomjee Roxana, Vilaplana Cristina, Yeboah-Manu Dorothy, Rasolof Voahangy, Munderi Paula, Singh Nalini, Aklillu Eleni, Padayatchi Nesri, Macete Eusebio, Kapata Nathan, Mulenga Modest, Kibiki Gibson, Mfinanga Sayoki, Nyirenda Thomas, Maboko Leonard, Garcia-Basteiro Alberto, Rakotosamimanana Niaina, Bates Matthew, Mwaba Peter, Reither Klaus, Gagneux Sebastien, Edwards Sarah, Mfinanga Elirehema, Abdulla Salim, Cardona Pere-Joan, Russell James B W, Gant Vanya, Noursadeghi Mahdad, Elkington Paul, Bonnet Maryline, Menendez Clara, Dieye Tandakha N, Diarra Bassirou, Maiga Almoustapha, Aseffa Abraham, Parida Shreemanta, Wejse Christian, Petersen Eskild, Kaleebu Pontiano, Oliver Matt, Craig Gill, Corrah Tumena, Tientcheu Leopold, Antonio Martin, Rao Martin, McHugh Timothy D, Sheikh Aziz, Ippolito Giuseppe, Ramjee Gita, Kaufmann Stefan H E, Churchyard Gavin, Steyn Andrie, Grobusch Martin, Sanne Ian, Martinson Neil, Madansein Rajhmun, Wilkinson Robert J, Mayosi Bongani, Schito Marco, Wallis Robert S. Towards host-directed therapies for tuberculosis.. Nature reviews. Drug discovery. 2015. DOI: 10.1038/nrd4696.

Предметные рубрики MeSH

Antitubercular AgentsDrug DesignDrug Therapy, CombinationHumansMolecular Targeted TherapyMycobacterium tuberculosisTuberculosis
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