Journal of multidisciplinary healthcare · 2026
Strategies for Managing Fluids and Electrolytes in High-Output Stomas: A Systematic Review and Evidence Summary.
СтатьяОбзорНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Wen Anna, Jiao Yanxia, Wang Ning, Xu Jie, Xu Xinyue, Du Li, Lv Lin
Аннотация
PURPOSE: This study aimed to explore intervention strategies for fluid and electrolyte regulation in patients with high-output stomas, to optimize their clinical outcomes and quality of life.
RESULTS: Fifteen experimental and semi-experimental studies were systematically reviewed. Interventions were categorized into five types by therapeutic purpose and route: gastrointestinal motility/anti-secretory agents, Glucagon-like Peptide-1/2 (GLP-1/2) analogs, rehydration/electrolyte supplements, micronutrient supplements, and dietary restriction. Key HOS complications included hyponatremia, hypomagnesemia, metabolic acidosis, hypokalemia, hypocalcemia, and kidney injury.
CONCLUSION: Hydro-electrolyte management in patients with HOS requires a multidisciplinary approach that integrates fluid management, pharmacotherapy, nutritional support, and surgical intervention. This framework may reduce dehydration-related readmission and improve outcomes. Future large-scale prospective studies are warranted to verify the efficacy, safety, and novel therapies, explore new therapeutic targets/drugs, and develop standardized guidelines, with an emphasis on individualized management for complex cases and prioritizing patient quality of life.
RESULTS: Fifteen experimental and semi-experimental studies were systematically reviewed. Interventions were categorized into five types by therapeutic purpose and route: gastrointestinal motility/anti-secretory agents, Glucagon-like Peptide-1/2 (GLP-1/2) analogs, rehydration/electrolyte supplements, micronutrient supplements, and dietary restriction. Key HOS complications included hyponatremia, hypomagnesemia, metabolic acidosis, hypokalemia, hypocalcemia, and kidney injury.
CONCLUSION: Hydro-electrolyte management in patients with HOS requires a multidisciplinary approach that integrates fluid management, pharmacotherapy, nutritional support, and surgical intervention. This framework may reduce dehydration-related readmission and improve outcomes. Future large-scale prospective studies are warranted to verify the efficacy, safety, and novel therapies, explore new therapeutic targets/drugs, and develop standardized guidelines, with an emphasis on individualized management for complex cases and prioritizing patient quality of life.