Nodular scleritis following alendronate therapy.

PURPOSE: To report a case of nodular scleritis following alendronate sodium.

METHODS

A 54 year-old male was treated with alendronate sodium 70 mg orally once per week. Eight weeks later, he experienced pain and redness of the right eye. Biomicroscopy was performed.

RESULTS

Patient was found to have inferonasal nodular scleritis. Laboratory work-up was unrevealing. Patient was given 4 mg of subtenon's triamcinolone acetate in the area of the nodular scleritis and had complete resolution. Two weeks following rechallenge with alendronate sodium resulted in recurrence of his scleritis.

CONCLUSION

Alendronate led to nodular scleritis and rechallenge caused recurrence of scleritis.