Mechanical thrombectomy for the treatment of primary and secondary anterior cerebral artery occlusions: insights from STAR.
Обработка статьи · этапы, ошибки и управление
Ошибки и ограничения
История · было → стало
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Dabhi Nisha, Kumar Jeyan Sathia, Ironside Natasha, Kellogg Ryan T, Sowlat Mohammad-Mahdi, Uchida Kazutaka, Maier Ilko, Al Kasab Sami, Jabbour Pascal, Kim Joon-Tae, Wolfe Stacey Q, Rai Ansaar, Starke Robert M, Psychogios Marios-Nikos, Samaniego Edgar A, Arthur Adam S, Yoshimura Shinichi, Cuellar Hugo, Howard Brian M, Alawieh Ali, Romano Daniele G, Tanweer Omar, Mascitelli Justin, Fragata Isabel, Polifka Adam J, Osbun Joshua W, Crosa Roberto Javier, Matouk Charles, Levitt Michael R, Brinjikji Waleed, Moss Mark, Dumont Travis M, Williamson Richard, Navia Pedro, Kan Peter, De Leacy Reade, Chowdhry Shakeel A, Ezzeldin Mohamad, Spiotta Alejandro M, Park Min S
Аннотация
METHODS: We performed a retrospective review of the multicenter Stroke Thrombectomy and Aneurysm (STAR) database. All patients with MT-treated primary or secondary ACA occlusions were included. Baseline characteristics, procedural outcomes, complications, and clinical outcomes were collected. Primary and secondary ACA occlusions were compared using the Mann-Whitney U test and Kruskal-Willis test for continuous variables and the χ2 test for categorical variables.
RESULTS: The study cohort comprised 238 patients with ACA occlusions (49.2% female, median (SD) age 65.6 (16.7) years). The overall rate of successful recanalization was 75%, 90-day good functional outcome was 23%, and 90-day mortality was 35%. There were 44 patients with a primary ACA occlusion and 194 patients with a secondary ACA occlusion. When adjusted for baseline variables, the rates of successful recanalization (68% vs 76%, P=0.27), 90-day good functional outcome (41% vs 19%, P=0.38), and mortality at 90 days (25% vs 38%, P=0.12) did not differ between primary and secondary ACA occlusion groups.
CONCLUSION: Clinical and procedural outcomes are similar between MT-treated primary and secondary ACA occlusions for select patients. Our findings demonstrate the need for established criteria to determine ideal patient and ACA stroke characteristics amenable to MT treatment.