American journal of ophthalmology case reports · 2019
Corneal ulceration associated with Nivolumab use.
Клинический случайСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Parker Jack S, Feagin Wyatt, Wang Christopher, Heersink Marius, Parker John S
Аннотация
PURPOSE: To describe a case of corneal ulceration associated with Nivolumab use.
OBSERVATIONS: An 80-year-old woman treated with Nivolumab for metastatic melanoma developed an intractable corneal ulcer in her left eye, refractory to all therapies - including surgery to cover the ulcer with a conjunctival flap - until topical prednisolone acetate was tried, which was curative.
CONCLUSIONS AND IMPORTANCE: Nivolumab use may be associated with a form of steroid-responsive corneal ulceration.
OBSERVATIONS: An 80-year-old woman treated with Nivolumab for metastatic melanoma developed an intractable corneal ulcer in her left eye, refractory to all therapies - including surgery to cover the ulcer with a conjunctival flap - until topical prednisolone acetate was tried, which was curative.
CONCLUSIONS AND IMPORTANCE: Nivolumab use may be associated with a form of steroid-responsive corneal ulceration.