Acta radiologica (Stockholm, Sweden : 1987) · 2008
Imaging features of helical computed tomography suggesting advanced urothelial carcinoma arising from the pelvocalyceal system.
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Kwak Kyung Won, Park Byung Kwan, Kim Chan Kyo, Lee Hyun Moo, Choi Han Yong
Аннотация
BACKGROUND: Urothelial carcinoma is the most common malignant tumor arising from the pelvocalyceal system. Helical computed tomography (CT) is probably the best preoperative-stage modality for the determination of treatment plan and prognosis.
PURPOSE: To obtain helical CT imaging features suggesting advanced pelvocalyceal urothelial carcinoma.
MATERIAL AND METHODS: Preoperative CT images in 44 patients with pelvocalyceal urothelial carcinoma were retrospectively reviewed and correlated with the pathological examination to determine imaging features suggesting stage III or IV of the disease.
RESULTS: Pathological stages revealed stage I in 16, stage II in three, stage III in 17, and stage IV in eight patients. Seven patients had metastatic lymph nodes. CT imaging showed that renal parenchymal invasion, sinus fat invasion, and lymph node metastasis were highly suggestive of advanced urothelial cell carcinoma (P<0.05). Helical CT sensitivity, specificity, and accuracy for advanced pelvocalyceal urothelial carcinoma were 76% (19/25), 84% (16/19), and 80% (35/44), respectively.
CONCLUSION: Preoperative helical CT may suggest imaging features of advanced urothelial carcinoma, influencing treatment plan and patient prognosis, even though its accuracy is not so high.
PURPOSE: To obtain helical CT imaging features suggesting advanced pelvocalyceal urothelial carcinoma.
MATERIAL AND METHODS: Preoperative CT images in 44 patients with pelvocalyceal urothelial carcinoma were retrospectively reviewed and correlated with the pathological examination to determine imaging features suggesting stage III or IV of the disease.
RESULTS: Pathological stages revealed stage I in 16, stage II in three, stage III in 17, and stage IV in eight patients. Seven patients had metastatic lymph nodes. CT imaging showed that renal parenchymal invasion, sinus fat invasion, and lymph node metastasis were highly suggestive of advanced urothelial cell carcinoma (P<0.05). Helical CT sensitivity, specificity, and accuracy for advanced pelvocalyceal urothelial carcinoma were 76% (19/25), 84% (16/19), and 80% (35/44), respectively.
CONCLUSION: Preoperative helical CT may suggest imaging features of advanced urothelial carcinoma, influencing treatment plan and patient prognosis, even though its accuracy is not so high.
Предметные рубрики MeSH
AdultAgedAged, 80 and overCarcinomaContrast MediaFemaleHumansIopamidolKidney CalicesKidney PelvisLymphatic MetastasisMaleMiddle AgedNeoplasm StagingRadiographic Image EnhancementReproducibility of ResultsRetrospective StudiesSensitivity and SpecificityTomography, Spiral ComputedUrologic NeoplasmsUrothelium