Endobronchial ultrasound guided transbronchial needle aspiration leading to cardiac empyema and tamponade by Prevotella oris.

Endobronchial ultrasound guided transbronchial needle aspiration (EBUS-TNBA) is widely recommended for the diagnosis of mediastinal lymphadenopathy of malignant and non-malignant aetiology. EBUS-TBNA is preferred over mediastinoscopy as it has a better diagnostic accuracy and safety, is cost-effective and less invasive. Major complications of EBUS-TBNA include bleeding, mediastinitis, pneumonia, mediastinal abscess, empyema, lung abscess, pericarditis, pneumothorax, and rarely pericardial tamponade. We report a patient who developed pericardial empyema and tamponade due to Prevotella oris following EBUS-TBNA.