JACC. Case reports · 2025
Cholesterol Pericarditis.
Клинический случайСтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
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Alam Mohammad Saquib, Zafar Khwaja Saifullah
Аннотация
BACKGROUND: Cholesterol pericarditis is a rare condition characterized by cholesterol crystal accumulation in the pericardium, often linked to hyperlipidemia and chronic inflammatory disorders.
CASE SUMMARY: A 50-year-old woman with a history of hypercholesterolemia presented with progressive dyspnea, chest pain, and fatigue. Clinical evaluation and imaging studies revealed a massive pericardial effusion. Pericardiocentesis was performed, and fluid analysis demonstrated the presence of cholesterol crystals. The patient was treated with pericardiocentesis, nonsteroidal anti-inflammatory drugs, and lipid-lowering therapy, leading to rapid symptom resolution.
DISCUSSION: Cholesterol pericarditis remains an underrecognized cause of pericardial effusion. A high index of suspicion is required in patients presenting with unexplained pericardial effusion. Diagnosis is primarily based on pericardial fluid analysis. Management includes symptomatic relief with pericardiocentesis, anti-inflammatory therapy, and long-term lipid control to prevent recurrence.
TAKE-HOME MESSAGES: Cholesterol pericarditis should be considered in patients with unexplained pericardial effusion and dyslipidemia. Early diagnosis and treatment can lead to favorable outcomes.
CASE SUMMARY: A 50-year-old woman with a history of hypercholesterolemia presented with progressive dyspnea, chest pain, and fatigue. Clinical evaluation and imaging studies revealed a massive pericardial effusion. Pericardiocentesis was performed, and fluid analysis demonstrated the presence of cholesterol crystals. The patient was treated with pericardiocentesis, nonsteroidal anti-inflammatory drugs, and lipid-lowering therapy, leading to rapid symptom resolution.
DISCUSSION: Cholesterol pericarditis remains an underrecognized cause of pericardial effusion. A high index of suspicion is required in patients presenting with unexplained pericardial effusion. Diagnosis is primarily based on pericardial fluid analysis. Management includes symptomatic relief with pericardiocentesis, anti-inflammatory therapy, and long-term lipid control to prevent recurrence.
TAKE-HOME MESSAGES: Cholesterol pericarditis should be considered in patients with unexplained pericardial effusion and dyslipidemia. Early diagnosis and treatment can lead to favorable outcomes.