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Orphanet journal of rare diseases · 2023

Post-acute phase and sequelae management of epidermal necrolysis: an international, multidisciplinary DELPHI-based consensus.

СтатьяПоддержка исследования: вне правительства СШАConsensus StatementНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
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Ingen-Housz-Oro S, Schmidt V, Ameri M M, Abe R, Brassard A, Mostaghimi A, Paller A S, Romano A, Didona B, Kaffenberger B H, Ben Said B, Thong B Y H, Ramsay B, Brezinova E, Milpied B, Mortz C G, Chu C Y, Sotozono C, Gueudry J, Fortune D G, Dridi S M, Tartar D, Do-Pham G, Gabison E, Phillips E J, Lewis F, Salavastru C, Horvath B, Dart J, Setterfield J, Newman J, Schulz J T, Delcampe A, Brockow K, Seminario-Vidal L, Jörg L, Watson M P, Gonçalo M, Lucas M, Torres M, Noe M H, Hama N, Shear N H, O'Reilly P, Wolkenstein P, Romanelli P, Dodiuk-Gad R P, Micheletti R G, Tiplica G S, Sheridan R, Rauz S, Ahmad S, Chua S L, Flynn T H, Pichler W, Le S T, Maverakis E, Walsh S, French L E, Brüggen M C

Аннотация

BACKGROUND: Long-term sequelae are frequent and often disabling after epidermal necrolysis (Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN)). However, consensus on the modalities of management of these sequelae is lacking.

OBJECTIVES: We conducted an international multicentric DELPHI exercise to establish a multidisciplinary expert consensus to standardize recommendations regarding management of SJS/TEN sequelae.

METHODS: Participants were sent a survey via the online tool "Survey Monkey" consisting of 54 statements organized into 8 topics: general recommendations, professionals involved, skin, oral mucosa and teeth, eyes, genital area, mental health, and allergy workup. Participants evaluated the level of appropriateness of each statement on a scale of 1 (extremely inappropriate) to 9 (extremely appropriate). Results were analyzed according to the RAND/UCLA Appropriateness Method.

RESULTS: Fifty-two healthcare professionals participated. After the first round, a consensus was obtained for 100% of 54 initially proposed statements (disagreement index < 1). Among them, 50 statements were agreed upon as 'appropriate'; four statements were considered 'uncertain', and ultimately finally discarded.

CONCLUSIONS: Our DELPHI-based expert consensus should help guide physicians in conducting a prolonged multidisciplinary follow-up of sequelae in SJS-TEN.

Предметные рубрики MeSH

ИП Урсолов Владлен Сергеевич

ИНН 500118482352 · ОГРНИП 314500117700049

Реквизиты и контакты