Evaluation of antibacterial and antiviral efficacy of volatile organic compounds.

This study searched for volatile organic compounds (VOCs）having antibacterial and antiviral efficacy. The antibacterial efficacy of volatilized components was evaluated and (2E,4E）-2,4-hexadienal, α- angelica lactone, 2-cyclohexen-1-one and 2-cyclopenten-1-one were found to inhibit the formation of colonies of Staphylococcus aureus and Escherichia coli. Evaluating the antimicrobial efficacy of the surfaces to which each VOC adhered to, these four compounds were revealed to have antibacterial efficacy (antibacterial activity value (A-value）against S. aureus; ≧2.63, A-value against Klebsiella pneumoniae; >5.07, A-value against E. coli; ≧2.17）. Furthermore, (2E,4E）-2,4-hexadienal and α-angelica lactone were found to have antiviral efficacy against Influenza A virus (H1N1）and Feline calicivirus on the cotton cloths to which it adheres to (antiviral activity value (R-value）against Influenza A virus; >2.94, R-value against Feline calicivirus; ≧2.31）. Using these components, it might be possible to develop antimicrobial products that exhibit antibacterial and antiviral efficacy.