Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology · 2005
[Effects of bFGF on the nasal mucosa after endoscopic sinus surgery].
Аннотация на английскомСтатьяРандомизированное исследованиеНазвание и аннотация: Перевод пока не подготовлен
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Mu Junshang, Zhang Xun, Cheng Jun, Yuan Yongyi
Аннотация
OBJECTIVE: To explore the effect of bFGF on nasal mucosa after ESS.
METHOD: Ten cases of type I phase 3 chronic sinusitis were selected randomly. For each patient bFGF was intranasally used in one single nasal cavity a week after ESS. The other cavity, treated with nothing, was used as control. Scanning electron microscopy examinations of middle meatus mucosa were made 1,1. 5, 2 and 3 month after ESS.
RESULT: In the first month after operation ciliated cells in the mucosa swelled and lined unregularly, the cilia exfoliated. From the sixth week to the 2nd month ciliated cells lined more regularly and the number of cells as well as the density of cilia increased obviously but the cilia aligned in disturbance. In the 3rd month after ESS, the swell of mucosa subside completely and cilia of columnar epithelial cells moved in one direction,which meant the cilia recover the function.
CONCLUSION: bFGF can speed up the recovery of nasal mucosa both in number and in function after ESS.
METHOD: Ten cases of type I phase 3 chronic sinusitis were selected randomly. For each patient bFGF was intranasally used in one single nasal cavity a week after ESS. The other cavity, treated with nothing, was used as control. Scanning electron microscopy examinations of middle meatus mucosa were made 1,1. 5, 2 and 3 month after ESS.
RESULT: In the first month after operation ciliated cells in the mucosa swelled and lined unregularly, the cilia exfoliated. From the sixth week to the 2nd month ciliated cells lined more regularly and the number of cells as well as the density of cilia increased obviously but the cilia aligned in disturbance. In the 3rd month after ESS, the swell of mucosa subside completely and cilia of columnar epithelial cells moved in one direction,which meant the cilia recover the function.
CONCLUSION: bFGF can speed up the recovery of nasal mucosa both in number and in function after ESS.