Journal of Alzheimer's disease reports · 2025
Adaptation and validations of Amsterdam instrumental activities of daily living questionnaire-short version for Peru.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Montesinos Rosa, Brown Gregory, Huilca José, Custodio Belén, Malaga Marco, Lipa Karol, Bustamante-Paytan Diego, Agüero Katherine, Verastegui Graciet, Yauri Zadith, Custodio Nilton
Аннотация
BACKGROUND: Instrumental Activities of Daily Living (IADL) are key indicators of functional decline in dementia, but culturally adapted tools for Latin America are scarce.
OBJECTIVE: This study aims to assess the validity and robustness of a new Peruvian version of the Amsterdam Instrumental Activities of Daily Living Questionnaire-Short Version (A-IADL-Q-SV-P).
METHODS: We recruited 171 participants from a cognitive clinic in Peru (81 Clinical Dementia Rating (CDR) = 0, 70 CDR = 1, 20 CDR = 2), including 54 with Alzheimer's disease and 36 with frontotemporal dementia. Validity of the A-IADL-Q-SV-P was assessed using quadratic discriminant analysis to classify CDR level. Spearman correlations tested robustness with demographics (age, sex, education) and associations with cognitive (Mini-Mental State Examination), mood (Generalized Anxiety Disorder-7, Geriatric Depression Scale, and Neuropsychiatric Inventory), and functionality (Pfeffer Functional Activities Questionnaire and Technology-Activities of Daily Living Questionnaire) measures.
RESULTS: The A-IADL-Q-SV-P achieved excellent accuracy for classifying dementia severity (accuracy: 0.853, AUC > 0.92). The ability to classify normal cognition had a sensitivity of 0.95 and a specificity of 0.91, and results were similar for patients with Alzheimer's disease or frontotemporal dementia (accuracy > 0.88, sensitivity > 0.95, and specificity > 0.88, AUC > 0.91). We also found weak associations with age, sex, and education (|rho| < 0.2). Furthermore, the A-IADL-Q-SV-P had strong associations with other clinical scales (|rho| > 0.4), particularly in relation to cognition (rho = -0.70) and functionality (rho > 0.87).
CONCLUSIONS: A-IADL-Q-SV-P demonstrated excellent accuracy in classifying dementia severity, with strong correlations to cognitive and other functionality measures. This supports the utility of A-IADL-Q-SV-P as a culturally adapted tool for assessing functional decline in dementia.
OBJECTIVE: This study aims to assess the validity and robustness of a new Peruvian version of the Amsterdam Instrumental Activities of Daily Living Questionnaire-Short Version (A-IADL-Q-SV-P).
METHODS: We recruited 171 participants from a cognitive clinic in Peru (81 Clinical Dementia Rating (CDR) = 0, 70 CDR = 1, 20 CDR = 2), including 54 with Alzheimer's disease and 36 with frontotemporal dementia. Validity of the A-IADL-Q-SV-P was assessed using quadratic discriminant analysis to classify CDR level. Spearman correlations tested robustness with demographics (age, sex, education) and associations with cognitive (Mini-Mental State Examination), mood (Generalized Anxiety Disorder-7, Geriatric Depression Scale, and Neuropsychiatric Inventory), and functionality (Pfeffer Functional Activities Questionnaire and Technology-Activities of Daily Living Questionnaire) measures.
RESULTS: The A-IADL-Q-SV-P achieved excellent accuracy for classifying dementia severity (accuracy: 0.853, AUC > 0.92). The ability to classify normal cognition had a sensitivity of 0.95 and a specificity of 0.91, and results were similar for patients with Alzheimer's disease or frontotemporal dementia (accuracy > 0.88, sensitivity > 0.95, and specificity > 0.88, AUC > 0.91). We also found weak associations with age, sex, and education (|rho| < 0.2). Furthermore, the A-IADL-Q-SV-P had strong associations with other clinical scales (|rho| > 0.4), particularly in relation to cognition (rho = -0.70) and functionality (rho > 0.87).
CONCLUSIONS: A-IADL-Q-SV-P demonstrated excellent accuracy in classifying dementia severity, with strong correlations to cognitive and other functionality measures. This supports the utility of A-IADL-Q-SV-P as a culturally adapted tool for assessing functional decline in dementia.