Somatosensory evoked potentials following posterior tibial nerve stimulation predict later motor outcome.

Posterior tibial nerve somatosensory evoked potentials (PTN-SEPs) were performed on 50 neonates at high risk of future neurodevelopmental impairment just before their discharge from the neonatal intensive-care unit. The close association of sensory pathways with motor tracts and the need for sensory input and integration for normal motor functioning would indicate that CNS lesions producing motor deficits may be detected by this method. Follow-up of these infants revealed a highly significant relationship between bilaterally abnormal PTN-SEPs and the presence of cerebral palsy at three years of age. Normal PTN-SEPs were associated with a normal outcome in 24 of 25 infants. In this group of neonates, PTN-SEPs were more predictive than cranial ultrasound.