The 730 nm Picosecond Titanium Sapphire Laser for Treatment of Kratom-Induced Hyperpigmentation.

OBJECTIVES

This case series reports the use of the 730-nm picosecond titanium-sapphire laser in the treatment of kratom-induced hyperpigmentation, a dermatological side effect associated with the use of Mitragyna speciosa, which remains poorly understood.

METHODS

A series of patients with kratom-induced hyperpigmentation were treated using the 730-nm picosecond titanium-sapphire laser. Treatment outcomes were documented by assessing the degree of pigmentation improvement and noting the occurrence of any adverse effects or recurrence of hyperpigmentation.

RESULTS

All patients showed significant improvement in the appearance of hyperpigmentation following treatment. No adverse effects or recurrence of hyperpigmentation were observed during the follow-up period.

CONCLUSIONS

This case series represents the first documented use of the 730-nm picosecond titanium-sapphire laser for treating kratom-induced hyperpigmentation. The laser's precision and minimal tissue disruption suggest it as a promising treatment option for this challenging dermatological side effect.