Japanese journal of ophthalmology · 2003
Ocular changes in a limited form of Wegener's granulomatosis: patient with cutaneous ulcer of upper eyelid.
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Kubota Toshinobu, Hirose Hiroshi
Аннотация
BACKGROUND: We report a patient with a limited form of Wegener's granulomatosis (WG) who presented with ocular changes and an eyelid ulcer in her left eye.
CASE: A 56-year-old woman complained of ocular pain and discharge. Upon examination, we found evidence of ulcerative keratitis, a mass in the orbit, and an eyelid skin ulcer in her left eye.
OBSERVATIONS: The antineutrophil cytoplasmic antibody test was negative, and systemic evaluations showed no specific changes. A biopsy specimen of the left orbit demonstrated necrosis, granulomatous inflammation, and vasculitis. A diagnosis was made of a limited form of WG, whilethe biopsy specimen of the left upper lid demonstrated granulomatous inflammation without vasculitis.
CONCLUSION: Although the eyelid ulcer was contiguous with the orbital mass, histopathology showed they had distinctive pathological features.
CASE: A 56-year-old woman complained of ocular pain and discharge. Upon examination, we found evidence of ulcerative keratitis, a mass in the orbit, and an eyelid skin ulcer in her left eye.
OBSERVATIONS: The antineutrophil cytoplasmic antibody test was negative, and systemic evaluations showed no specific changes. A biopsy specimen of the left orbit demonstrated necrosis, granulomatous inflammation, and vasculitis. A diagnosis was made of a limited form of WG, whilethe biopsy specimen of the left upper lid demonstrated granulomatous inflammation without vasculitis.
CONCLUSION: Although the eyelid ulcer was contiguous with the orbital mass, histopathology showed they had distinctive pathological features.