The American journal of gastroenterology · 2020
Normal Lactate and Unenhanced CT-Scan Result in Delayed Diagnosis of Acute Mesenteric Ischemia.
СтатьяНаблюдательное исследованиеПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен
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Nuzzo Alexandre, Joly Francisca, Ronot Maxime, Castier Yves, Huguet Audrey, Paugam-Burtz Catherine, Cazals-Hatem Dominique, Tran-Dinh Alexy, Becq Aymeric, Panis Yves, Bouhnik Yoram, Maggiori Leon, Corcos Olivier, SURVI group
Аннотация
INTRODUCTION: To investigate the factors associated with a delayed diagnosis (DD) of acute mesenteric ischemia (AMI).
METHODS: An observational cohort study from an intestinal failure center. The primary outcome was DD >24 hours.
RESULTS: Between 2006 and 2015, 74 patients with AMI were included and 39 (53%) had a DD. Plasma lactate <2 mmol/L (odd ratio: 3.2; 95% confidence interval: 1.1-9.1; P = 0.03) and unenhanced computed tomography scan (odds ratio: 5.9; 95% confidence interval: 1.4-25.8; P = 0.01) were independently associated with DD.
DISCUSSION: Suspicion of AMI should no longer be affected by normal plasma lactate levels and should prompt evaluation by a contrast-enhanced computed tomography-scan.
METHODS: An observational cohort study from an intestinal failure center. The primary outcome was DD >24 hours.
RESULTS: Between 2006 and 2015, 74 patients with AMI were included and 39 (53%) had a DD. Plasma lactate <2 mmol/L (odd ratio: 3.2; 95% confidence interval: 1.1-9.1; P = 0.03) and unenhanced computed tomography scan (odds ratio: 5.9; 95% confidence interval: 1.4-25.8; P = 0.01) were independently associated with DD.
DISCUSSION: Suspicion of AMI should no longer be affected by normal plasma lactate levels and should prompt evaluation by a contrast-enhanced computed tomography-scan.
Предметные рубрики MeSH
Abdominal PainAcute DiseaseAdultAnastomosis, SurgicalChronic DiseaseCohort StudiesColonContrast MediaDelayed DiagnosisEarly DiagnosisEarly Medical InterventionFemaleHumansIntestine, SmallJejunostomyLactic AcidMaleMesenteric IschemiaMiddle AgedRetrospective StudiesRisk FactorsShort Bowel SyndromeTomography, X-Ray ComputedVomiting