Life (Basel, Switzerland) · 2024
The Relationship Between the Kansas City Cardiomyopathy Questionnaire and Electrocardiographic Parameters in Predicting Outcomes After Cardiac Resynchronization Therapy.
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Rosu Andrei-Mihnea, Tomescu Luminita-Florentina, Badea Theodor-Georgian, Radu Emanuel-Stefan, Rosu Andreea-Liana, Brezeanu Lavinia-Nicoleta, Tanasescu Maria-Daniela, Isac Sebastian, Isac Teodora, Popa Oana-Andreea, Sinescu Crina-Julieta
Аннотация
BACKGROUND: Cardiac resynchronization therapy (CRT) is an essential treatment for patients with symptomatic heart failure and ventricular conduction abnormalities. Low-ejection-fraction (EF) cardiomyopathy often involves a wide QRS complex displaying a left bundle branch block (LBBB) morphology and markedly delayed activation of the LV lateral wall. Following CRT, patients with heart failure and LBBB have better outcomes and quality-of-life improvements. Various electrocardiographic and clinical parameters are thought to be able to predict this improvement. The Kansas City Cardiomyopathy Questionnaire (KCCQ) is a reliable tool for measuring these patients' quality of life.
METHODS: This is an observational prospective study featuring over 69 individuals diagnosed with cardiac failure and dilatative cardiomyopathy with low-EF and major LBBB. This study analyzed the correlations between patient outcomes and demographic, clinical, and electrocardiographic parameters.
RESULTS: Following the analysis, we observed correlations between the QRS area, intraprocedural systolic blood pressure, Q-LV interval, the R-wave amplitude in the right precordial leads and the CRT outcomes indicated by the KCCQ score.
CONCLUSIONS: The parameters found and their correlation with the KCCQ score show how CRT therapy impacts patients' quality of life, symptom burden, and functional status.
METHODS: This is an observational prospective study featuring over 69 individuals diagnosed with cardiac failure and dilatative cardiomyopathy with low-EF and major LBBB. This study analyzed the correlations between patient outcomes and demographic, clinical, and electrocardiographic parameters.
RESULTS: Following the analysis, we observed correlations between the QRS area, intraprocedural systolic blood pressure, Q-LV interval, the R-wave amplitude in the right precordial leads and the CRT outcomes indicated by the KCCQ score.
CONCLUSIONS: The parameters found and their correlation with the KCCQ score show how CRT therapy impacts patients' quality of life, symptom burden, and functional status.