Journal of the European Academy of Dermatology and Venereology : JEADV · 2009
Is there any relation between serum insulin and insulin-like growth factor-I in non-diabetic patients with skin tag?
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Jowkar F, Fallahi A, Namazi M R
Аннотация
BACKGROUND: Skin tags are common benign lesion occurring mainly on the neck and major flexures as a small soft pedunculated protrusion. This study evaluate insulin and insulin-like growth factor-I (IGF-I) in non-diabetic ones.
METHODS AND MATERIALS: A case-control study was conducted in non-diabetic persons. Comparing insulin and IGF-I between matched cases (n = 40) and controls (n = 40) by radioimmunoassay test. Cases and controls were recruited from patients consecutively seen at an academic outpatient dermatology clinic.
RESULTS: The insulin level in patients with skin tags was significantly higher than controls (P = 0.00) but IGF-I level was not significantly different (P = 0.43).
CONCLUSION: These results show an increased insulin level in non-diabetics ones and overall importance of insulin effect in pathogenesis of skin tags.
METHODS AND MATERIALS: A case-control study was conducted in non-diabetic persons. Comparing insulin and IGF-I between matched cases (n = 40) and controls (n = 40) by radioimmunoassay test. Cases and controls were recruited from patients consecutively seen at an academic outpatient dermatology clinic.
RESULTS: The insulin level in patients with skin tags was significantly higher than controls (P = 0.00) but IGF-I level was not significantly different (P = 0.43).
CONCLUSION: These results show an increased insulin level in non-diabetics ones and overall importance of insulin effect in pathogenesis of skin tags.