Journal of the American Academy of Dermatology · 1998
Bath-PUVA therapy in three patients with scleredema adultorum.
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Hager C M, Sobhi H A, Hunzelmann N, Wickenhauser C, Scharenberg R, Krieg T, Scharffetter-Kochanek K
Аннотация
BACKGROUND: Scleredema adultorum (SA) is a rare connective tissue disorder for which no treatment has proven to be effective.
OBJECTIVE: Our purpose was to determine the effect of bath-PUVA therapy on SA.
METHODS: Three patients were treated. Clinical evaluation of skin induration and thickness as well as ultrasonography were performed at baseline and after treatment.
RESULTS: All three patients showed substantial clinical improvement with bath-PUVA therapy (median of 59 treatments and a cumulative UVA dose of 245.7 J/cm2). Ultrasonography showed significant reduction in both skin thickness and density.
CONCLUSION: Bath-PUVA therapy appears to be effective in the treatment of SA.
OBJECTIVE: Our purpose was to determine the effect of bath-PUVA therapy on SA.
METHODS: Three patients were treated. Clinical evaluation of skin induration and thickness as well as ultrasonography were performed at baseline and after treatment.
RESULTS: All three patients showed substantial clinical improvement with bath-PUVA therapy (median of 59 treatments and a cumulative UVA dose of 245.7 J/cm2). Ultrasonography showed significant reduction in both skin thickness and density.
CONCLUSION: Bath-PUVA therapy appears to be effective in the treatment of SA.