Ophthalmology · 2010
Stromal support for Descemet's membrane endothelial keratoplasty.
СтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
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Ошибки и ограничения
История · было → стало
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Busin Massimo, Patel Amit K, Scorcia Vincenzo, Galan Alessandro, Ponzin Diego
Аннотация
PURPOSE: To evaluate the use of a peripheral stromal support to facilitate and improve the outcomes of Descemet's membrane endothelial keratoplasty (DMEK).
DESIGN: Prospective case series.
PARTICIPANTS: Ten patients with Fuchs' endothelial dystrophy.
INTERVENTION: Pneumatic dissection was used to detach the central part of the Descemet's membrane and endothelium from the deep stroma. Endothelial grafts including a peripheral stromal support were obtained by eccentric punching of donor tissue and used to perform DMEK surgery in 10 patients.
MAIN OUTCOME MEASURES: Operative time, graft attachment rate, best spectacle-corrected visual acuity (BSCVA), endothelial cell loss, refraction, and complications.
RESULTS: In all cases the surgical time was ≤ 1 hour. The postoperative course was uneventful in all but 2 cases, which required rebubbling owing to early graft detachment. Final attachment rate was 100%. The average follow-up was 8.4 months (range, 6-12). Postoperative BSCVA was ≥ 20/40 in all cases and no substantial change in refraction was recorded. Postoperative endothelial cell loss averaged 24.1% (range, 8%-34.9%).
CONCLUSIONS: Stromal support facilitates surgery, reduces complications, and appears to maintain the favorable outcomes of DMEK.
DESIGN: Prospective case series.
PARTICIPANTS: Ten patients with Fuchs' endothelial dystrophy.
INTERVENTION: Pneumatic dissection was used to detach the central part of the Descemet's membrane and endothelium from the deep stroma. Endothelial grafts including a peripheral stromal support were obtained by eccentric punching of donor tissue and used to perform DMEK surgery in 10 patients.
MAIN OUTCOME MEASURES: Operative time, graft attachment rate, best spectacle-corrected visual acuity (BSCVA), endothelial cell loss, refraction, and complications.
RESULTS: In all cases the surgical time was ≤ 1 hour. The postoperative course was uneventful in all but 2 cases, which required rebubbling owing to early graft detachment. Final attachment rate was 100%. The average follow-up was 8.4 months (range, 6-12). Postoperative BSCVA was ≥ 20/40 in all cases and no substantial change in refraction was recorded. Postoperative endothelial cell loss averaged 24.1% (range, 8%-34.9%).
CONCLUSIONS: Stromal support facilitates surgery, reduces complications, and appears to maintain the favorable outcomes of DMEK.
Предметные рубрики MeSH
AgedCorneal Endothelial Cell LossCorneal StromaCorneal TransplantationDescemet MembraneEndothelium, CornealFemaleFollow-Up StudiesFuchs' Endothelial DystrophyGraft SurvivalHumansIntraoperative ComplicationsMaleMiddle AgedPostoperative ComplicationsProspective StudiesRefraction, OcularTime FactorsVisual Acuity