Retinal cases & brief reports · 2026
A CASE OF UVEAL MELANOMA MASQUERADING AS CHOROIDAL LYMPHOMA.
СтатьяКлинический случайНазвание и аннотация: Перевод пока не подготовлен
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Saleh Sahal H, Stepanian Rima, Juliano Joseph D, Folberg Robert, Laurie Lau-Sickon, Faia Lisa J, Weiner Adam J
Аннотация
PURPOSE: To present a case of uveal melanoma masquerading as choroidal lymphoma.
METHODS: A retrospective case report in which medical and imaging records, including fundus photography, optical coherence tomography, fundus autofluorescence, fluorescein angiography, and ultrasonography, were reviewed.
RESULTS: A 77-year-old woman presenting with decreased vision was found to have a diffuse, shallow, yellow choroidal mass associated with retinal pigment epithelium pigmentary changes and exudative detachment in her right eye. Multimodal imaging demonstrated thickened choroid with a "lumpy-bumpy" appearance on optical coherence tomography, "leopard-spotting" on fundus autofluorescence, and a shallow "table-top" configuration on B scan. Systemic workup was unremarkable. The patient elected to undergo treatment with low-dose external beam radiation for presumed choroidal lymphoma. There was no response to radiation prompting retinochoroidal biopsy, which revealed spindle-cell uveal melanoma and resulted in enucleation.
CONCLUSION: We present a case of uveal melanoma masquerading as choroidal lymphoma. This case highlights that uveal melanoma can rarely masquerade as other entities, including uveal lymphoma.
METHODS: A retrospective case report in which medical and imaging records, including fundus photography, optical coherence tomography, fundus autofluorescence, fluorescein angiography, and ultrasonography, were reviewed.
RESULTS: A 77-year-old woman presenting with decreased vision was found to have a diffuse, shallow, yellow choroidal mass associated with retinal pigment epithelium pigmentary changes and exudative detachment in her right eye. Multimodal imaging demonstrated thickened choroid with a "lumpy-bumpy" appearance on optical coherence tomography, "leopard-spotting" on fundus autofluorescence, and a shallow "table-top" configuration on B scan. Systemic workup was unremarkable. The patient elected to undergo treatment with low-dose external beam radiation for presumed choroidal lymphoma. There was no response to radiation prompting retinochoroidal biopsy, which revealed spindle-cell uveal melanoma and resulted in enucleation.
CONCLUSION: We present a case of uveal melanoma masquerading as choroidal lymphoma. This case highlights that uveal melanoma can rarely masquerade as other entities, including uveal lymphoma.