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DOI 10.1093/mr/roaf023

Медицинская библиотека · Modern rheumatology · 2025

Oral health-related quality of life in Sjögren's disease patients with unstimulated whole salivary flows ≥0.1 ml/min for whom no therapeutic approaches are provided in the EULAR recommendations.

Azuma Naoto, Iwatani Maki, Yokoyama Yuichi, Hashimoto Naoaki, Tamura Masao, Hashimoto Teppei, Morimoto Mai, Nishioka Aki, Kitano Masayasu, Tsunoda Shinichiro, Yamane Takashi, Matsui Kiyoshi, Sano Hajime

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Аннотация

OBJECTIVES

To assess the oral health-related quality of life (OHRQoL) in Sjögren's disease (SjD) patients with unstimulated whole salivary flow (UWSF) ≥0.1 ml/min for whom no preferred therapeutic approaches are provided in the European League Against Rheumatism recommendations.

METHODS

Thirty-four SjD patients and 23 controls were enrolled in this study. The UWSF was measured using the spitting method. OHRQoL was quantitatively evaluated using the short-form Oral Health Impact Profile (OHIP-14).

RESULTS

In SjD patients, 26 (76.5%) had a UWSF <0.1 ml/min, and 8 (23.5%) had ≥0.1 ml/min. The OHIP-14 scores were significantly higher in both the ≥0.1 and <0.1 ml/min groups than in the non-SjD group. Among the OHIP-14 questions, the ≥0.1 ml/min group scored significantly higher than the non-SjD group for 'uncomfortable to eat foods', 'self-conscious', 'diet unsatisfactory', 'difficult to relax', 'felt life less satisfying', and 'unable to function'.

CONCLUSIONS

Even with UWSF ≥0.1 ml/min, SjD patients had lower OHRQoL. The normal range of salivary flow rates is wide, exhibiting high interindividual variability. Even if the salivary flow rate is preserved in a single measurement, the possibility of having oral dryness due to a decrease in the salivary flow rate from the normal value for that patient should be considered.

Для цитирования: Azuma Naoto, Iwatani Maki, Yokoyama Yuichi, Hashimoto Naoaki, Tamura Masao, Hashimoto Teppei, Morimoto Mai, Nishioka Aki, Kitano Masayasu, Tsunoda Shinichiro, Yamane Takashi, Matsui Kiyoshi, Sano Hajime. Oral health-related quality of life in Sjögren's disease patients with unstimulated whole salivary flows ≥0.1 ml/min for whom no therapeutic approaches are provided in the EULAR recommendations.. Modern rheumatology. 2025. DOI: 10.1093/mr/roaf023.

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