[Study progress on hepatitis E].

10%-20% of acute clinical sporatic hepatitis is hepatitis E (HE). HE has a severe diaease low mortality in general population of about 0.5-1.5%. It has been reported as severe disease and the mortality increased to 20% in pregnant women and old people. China is high-epidemic for hepatitis E virus (HEV). HEV is mainly transmitted through faecal-oral route, data also showed that HEV could be transferred through blood donation. The epidemiology, diagnostics and vaccine development of HE is reviewed in this paper.