Dopaminergic treatments for hyperprolactinaemia.

Hyperprolactinaemia is a frequent cause of anovulatory sterility, although spontaneous pregnancy may occur occasionally. Dopaminergic treatment is highly effective for the treatment of both idiopathic and tumoral hyperprolactinaemia. If the only cause of infertility is chronic anovulation due to hyperprolactinaemia, an 80% pregnancy rate can be anticipated. Because of these results, surgical treatment is still needed only rarely. Pregnancy, either spontaneous or drug-related, is usually uneventful for the mother and is not associated with any increase in abortion, twins or malformations. Pregnancy-related tumour growth occurs rarely and can be treated successfully with dopaminergic drugs. On the contrary, there is more frequently improvement after pregnancy of the biochemical and clinical disorders associated with hyperprolactinaemia.