Loxapine for the treatment of psychosis in Lewy body dementia: A case report.

Lewy body dementia (LBD) is a progressive neurological disorder characterized by dementia, parkinsonism, and psychotic symptoms. Treating psychosis in LBD is particularly challenging, especially given the high risk of extrapyramidal effects of antipsychotics commonly associated with this population. If treatment with an antipsychotic is warranted, low-potency antipsychotics are preferred; however, they may not be suitable for all patients because of adverse effect profiles, safety concerns, or logistical barriers. This case study illustrates how a patient diagnosed with LBD and unable to tolerate or access commonly used antipsychotics was effectively treated with low-dose loxapine.