Internal medicine (Tokyo, Japan) · 2018
Multiple Synchronous Sporadic Gastrointestinal Stromal Tumors in the Stomach and Jejunum.
Клинический случайСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Tokunaga Mami, Nanjo Sohachi, Yoshita Hiroki, Fujinami Haruka, Watanabe Tohru, Ishii Yoko, Kobayashi Saito, Akashi Momoko, Takagi Hiroaki, Mihara Hiroshi, Kajiura Shinya, Ando Takayuki, Hashimoto Isaya, Hojo Shozo, Okumura Tomoyuki, Sugiyama Toshiro
Аннотация
A 77-year-old patient was admitted to our hospital for the further examination of melena. A computed tomography scan detected two submucosal tumors (SMTs) in the stomach and jejunum. Double-balloon endoscopy revealed the presence of a delle on the jejunal SMT, suggesting that the SMT was the origin of the gastrointestinal bleeding. Both tumors were surgically resected and subsequently diagnosed via histology as gastrointestinal stromal tumors (GISTs). Furthermore, the two GISTs had different mutations in the c-kit gene, suggesting that they were derived from different clonal origins. This report depicts an extremely rare case of multiple synchronous sporadic GISTs in the stomach and jejunum.