Impact of preoperative visceral fat proportion on type 2 diabetes in patients with low body mass index after gastrectomy.

BACKGROUND

Metabolic surgery is an effective option for treatment of type 2 diabetes. Although body mass index (BMI) has several limitations in differentiating the metabolic risks of the same weight of muscle and fat, it is used as the basis of indication for metabolic surgery.

OBJECTIVES

Since visceral fat is highly associated with metabolic disease, we evaluated the effectiveness of visceral fat proportion (VFP) for predicting metabolic risk preoperatively.

SETTING

University hospital.

METHODS

Fifty-two type 2 diabetes patients with BMI≤35 kg/cm2 who underwent gastrectomy for gastric cancer were included. Pre- and postoperative VFPs were measured using abdominal computed tomography. Multivariate logistic regression analysis was performed to estimate the effect of VFP on type 2 diabetes. Receiver operating curve analysis was used to estimate the effectiveness of VFP as a predictor of type 2 diabetes improvement.

RESULTS

Thirty-three of the 52 patients (63%) showed improved type 2 diabetes postoperatively. Low preoperative VFP (odds ratio [OR] = .913; 95% confidence interval [CI] = .835-.999; P = .048) and low glycated hemoglobin level (OR = .357; 95% CI = .172-.742; P = .006) were associated with type 2 diabetes improvement 2 years after gastrectomy. The area under the curve was 70.2%, indicating moderate accuracy.

CONCLUSIONS

Preoperative VFP might be a reasonable predictive factor for type 2 diabetes improvement after gastrectomy for patients with a BMI≤35 kg/cm2. High-quality studies of visceral fat for metabolic function are needed in the future.