Immunoreactivity to material like vasoactive intestinal polypeptide in epidermal cells of lichen sclerosus et atrophicus.

Immunoreactivity to material like vasoactive intestinal polypeptide was found to occur within certain cellular elements of the epidermis in two patients out of four who had lesions of lichen sclerosus et atrophicus. No specific immunofluorescence to the material could be seen in the dermis, apart from single immunoreactive nerve fibers.