Unusual interstitial deletion of the 8q12 band in a case of acute monocytic leukemia.

The authors describe a case of acute monocytic leukemia with a clonal deletion of the 8q12 band as a single chromosomal aberration. On the basis of this and other reports from the literature, they suggest that the 8q1 region, hitherto considered significantly involved in solid tumors, may be important also for hematologic malignancies.