Ophthalmology science · 2025
Lacquer Cracks Detection and Measurement Using Black-on-White Infrared Reflectance and Late-Phase Indocyanine Green Angiography in Pathologic Myopia.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Girolamo Matteo Maria, Crincoli Emanuele, Amoroso Francesca, Estrada-Walker Juliana, Querques Giuseppe, Souied Eric H, Miere Alexandra
Аннотация
PURPOSE: The aim of this study is to compare the detection and quantification of lacquer cracks (LCs) using 2 imaging methods: indocyanine green angiography (ICGA) and black-on-white infrared reflectance (bwIR).
DESIGN: Retrospective single-center study.
SUBJECTS: Myopic patients diagnosed with LCs at the Department of Ophthalmology of the University Paris Est Créteil.
METHODS: Medical records and multimodal imaging, including bwIR and ICGA, of myopic patients aged >18 years with LCs were reviewed. Two independent graders evaluated the presence of LCs in bwIR images and on late-phase ICGA. Image processing was used to segment and compute the area of LCs on bwIR and ICGA.
MAIN OUTCOME MEASURES: Evaluation and comparison of the rate of detection of LCs on bwIR and late-phase ICGA. Comparison between the extent of LCs detected by bwIR and with late-phase ICGA.
RESULTS: Thirty-two (32) eyes of 22 patients (13 women, 9 men) with a mean age of 54.95 ± 18.7 years were included in this study. Graders detected LCs on bwIR images in 29/32 analyzed cases (90.6% sensitivity, 95% CI: 75%-98%), whereas they detected LCs in 32/32 cases in ICGA images (100% sensitivity). Agreement between graders in detection was very good (Cohen κ = 0.78). The mean area of the LCs detected in bwIR images was 14.58 ± 8.21 mm2, whereas the mean area of the LCs in ICGA was 13.86 ± 8.50 mm2. This difference was not statistically significant in paired analysis (P = 0.73).
CONCLUSIONS: In this study, we propose rapid and noninvasive bwIR as a valid and promising noninvasive screening tool for detection of LCs and quantifying their extension.
FINANCIAL DISCLOSURES: Proprietary or commercial disclosure may be found in the Footnotes and Disclosures at the end of this article.
DESIGN: Retrospective single-center study.
SUBJECTS: Myopic patients diagnosed with LCs at the Department of Ophthalmology of the University Paris Est Créteil.
METHODS: Medical records and multimodal imaging, including bwIR and ICGA, of myopic patients aged >18 years with LCs were reviewed. Two independent graders evaluated the presence of LCs in bwIR images and on late-phase ICGA. Image processing was used to segment and compute the area of LCs on bwIR and ICGA.
MAIN OUTCOME MEASURES: Evaluation and comparison of the rate of detection of LCs on bwIR and late-phase ICGA. Comparison between the extent of LCs detected by bwIR and with late-phase ICGA.
RESULTS: Thirty-two (32) eyes of 22 patients (13 women, 9 men) with a mean age of 54.95 ± 18.7 years were included in this study. Graders detected LCs on bwIR images in 29/32 analyzed cases (90.6% sensitivity, 95% CI: 75%-98%), whereas they detected LCs in 32/32 cases in ICGA images (100% sensitivity). Agreement between graders in detection was very good (Cohen κ = 0.78). The mean area of the LCs detected in bwIR images was 14.58 ± 8.21 mm2, whereas the mean area of the LCs in ICGA was 13.86 ± 8.50 mm2. This difference was not statistically significant in paired analysis (P = 0.73).
CONCLUSIONS: In this study, we propose rapid and noninvasive bwIR as a valid and promising noninvasive screening tool for detection of LCs and quantifying their extension.
FINANCIAL DISCLOSURES: Proprietary or commercial disclosure may be found in the Footnotes and Disclosures at the end of this article.