Preventive medicine · 2025
Association between adolescent overweight and adult mortality risk: A systematic review.
СтатьяСистематический обзорНазвание и аннотация: Перевод пока не подготовлен
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Aguiar Barbara Cristina Cruz, Gonçalves Tatiana Rehder, Leite Tatiana Henriques, Blaudt Luana Senna, Barros Lorrayne Santiago Machado de, Oliveira Laís Silva de, Macedo Laylla Ribeiro, Souza Amanda de Moura
Аннотация
OBJECTIVE: This systematic review examined the association between adolescent overweight and all-cause and cause-specific mortality in adulthood.
METHODS: We searched for studies published between 2014 and 2024 that included adults (aged 20 years or older) who had been classified as having overweight and/or obesity during adolescence (aged 10 to 19 years). PubMed, Embase, Scopus, BVS/LILACS, and SciELO were searched between April and May 2024. Two reviewers independently performed study selection, data extraction, and risk-of-bias assessments.
RESULTS: Eighteen of the 1256 records screened met the eligibility criteria. All studies used a cohort design, and most of them were conducted in high-income countries, with a median follow-up of 30 years. A consistent positive association was found between adolescent obesity and increased all-cause mortality in adulthood, particularly related to cardiovascular diseases. Hazard ratios for all-cause mortality ranged from 1.3 to 2.7, with higher risks observed among adolescents with severe obesity. Most studies (70 %) were classified as having high methodological quality, reflecting strong methodological rigor and a low risk of bias. Heterogeneity among studies precluded a meta-analysis.
CONCLUSIONS: Since adolescent obesity is a strong predictor of premature adult mortality, early prevention and intervention strategies in this age group may help reduce long-term mortality risk.
METHODS: We searched for studies published between 2014 and 2024 that included adults (aged 20 years or older) who had been classified as having overweight and/or obesity during adolescence (aged 10 to 19 years). PubMed, Embase, Scopus, BVS/LILACS, and SciELO were searched between April and May 2024. Two reviewers independently performed study selection, data extraction, and risk-of-bias assessments.
RESULTS: Eighteen of the 1256 records screened met the eligibility criteria. All studies used a cohort design, and most of them were conducted in high-income countries, with a median follow-up of 30 years. A consistent positive association was found between adolescent obesity and increased all-cause mortality in adulthood, particularly related to cardiovascular diseases. Hazard ratios for all-cause mortality ranged from 1.3 to 2.7, with higher risks observed among adolescents with severe obesity. Most studies (70 %) were classified as having high methodological quality, reflecting strong methodological rigor and a low risk of bias. Heterogeneity among studies precluded a meta-analysis.
CONCLUSIONS: Since adolescent obesity is a strong predictor of premature adult mortality, early prevention and intervention strategies in this age group may help reduce long-term mortality risk.