[The course of the disease and the effectiveness of chemotherapy in patients with bipolar disorder and the indicators of organic brain damage in psychological tests].

The work is the part of the investigations on central nervous system condition in bipolar patients and on the correlation between structural changes in central nervous system and the course of the disease as well as the pharmacotherapy efficacy. By use the psychological battery (WAIS, Benton Gestalt Test, L. Bender test) 19 male and 13 female bipolar patients (total 32) with at least 10 years lasting course of the disease were studied. Patients mean age was 52.4. Patients were evaluated during remission or during the subdepressive phase. The statistical analysis revealed significant correlation only between the indexes of central nervous system organic damage in psychological evaluation and the age and length of the disease.