Can Atopic Dermatitis and Allergic Contact Dermatitis Coexist?

Due to their seemingly divergent immune pathways, it previously was thought that atopic dermatitis (AD) and allergic contact dermatitis (ACD) could not occur together. However, novel research suggests that the 2 conditions may be more closely related than previously understood. Herein, we discuss the overlapping relationship between AD and ACD and review the evidence for their coexistence. We also review management strategies to consider for patients with dual diagnoses of AD and ACD.