Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2008
Vertebrobasilar revascularization rates and outcomes in the MERCI and multi-MERCI trials.
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Lutsep Helmi L, Rymer Marilyn M, Nesbit Gary M
Аннотация
OBJECTIVE: Mortality of 40% to 86% and good outcomes in only 13% to 21% of patients beg for treatment options for basilar occlusion. This study determined outcomes of patients with vertebrobasilar occlusion treated with mechanical embolus removal in cerebral ischemia (MERCI) retriever mechanical thrombectomy.
METHODS: Patients with vertebrobasilar occlusion in the MERCI and Multi-MERCI trials received treatment up to 8 hours after symptom onset. Recanalization was determined after retriever use and adjunctive therapy. Mortality and good outcomes, modified Rankin scale score 0-3, were determined at 90 days in patients who were recanalized and not recanalized.
RESULTS: Recanalization occurred in 21 of 27 (78%) patients. Mortality was 44% and good outcomes were seen in 41%. Patients with recanalization tended to have better outcomes than those without.
CONCLUSIONS: Outcomes in patients with vertebrobasilar occlusions treated with the MERCI retriever compared favorably with natural history reports and tended to be better in those patients with recanalization.
METHODS: Patients with vertebrobasilar occlusion in the MERCI and Multi-MERCI trials received treatment up to 8 hours after symptom onset. Recanalization was determined after retriever use and adjunctive therapy. Mortality and good outcomes, modified Rankin scale score 0-3, were determined at 90 days in patients who were recanalized and not recanalized.
RESULTS: Recanalization occurred in 21 of 27 (78%) patients. Mortality was 44% and good outcomes were seen in 41%. Patients with recanalization tended to have better outcomes than those without.
CONCLUSIONS: Outcomes in patients with vertebrobasilar occlusions treated with the MERCI retriever compared favorably with natural history reports and tended to be better in those patients with recanalization.
Предметные рубрики MeSH
AdultAgedAged, 80 and overEquipment DesignFemaleFibrinolytic AgentsHumansInfusions, IntravenousMaleMiddle AgedMulticenter Studies as TopicRandomized Controlled Trials as TopicRecovery of FunctionSeverity of Illness IndexStrokeThrombectomyThrombolytic TherapyTime FactorsTissue Plasminogen ActivatorTreatment OutcomeVascular PatencyVertebrobasilar Insufficiency