Journal of cataract and refractive surgery · 2005
Six-month variability of the dark-adapted pupil diameter.
СтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Khanani Arshad M, Brown Sandra M, Xu Ke Tom
Аннотация
PURPOSE: To determine the individual variability of the dark-adapted pupil diameter over 6 months using a standardized dark-adaptation protocol.
SETTING: Texas Tech University Health Sciences Center, Lubbock, Texas, USA.
METHODS: This prospective observational cohort study comprised volunteers with no history of ocular disease, surgery, or injury other than requirement for refractive correction. The right eye was tested. A standardized dark-adaptation protocol was used that controlled for accommodation and patient alertness. Infrared, still digital photographs were taken after 10 minutes of dark adaptation at 1 lux and were analyzed using digital image software. Testing was performed at baseline in the afternoon, at 3 months in the afternoon, and at 6 months in the morning. Lifestyle factors such as diet and exercise were not controlled.
RESULTS: Mean intersession differences were 0.04 mm (95% confidence interval [CI]: -0.68-0.146), 0.15 mm (95% CI: -0.001-0.297), and 0.09 mm (95% CI: -0.048-0.236) for baseline-3 month, baseline-6 month, and 3 month-6 month comparisons, respectively. None of these differences was significantly different from zero (P>.05, 2-tailed Student t tests). The likelihood that the mean intersession difference was >.25 mm was negligible for all comparisons (P=.9996, .9099, and .9829 respectively, 1-tailed Student t tests).
CONCLUSION: When a consistent dark-adaptation protocol that controls for alertness and accommodation is used, normal young individuals showed no significant variation in the dark-adapted pupil diameter over a 6-month period.
SETTING: Texas Tech University Health Sciences Center, Lubbock, Texas, USA.
METHODS: This prospective observational cohort study comprised volunteers with no history of ocular disease, surgery, or injury other than requirement for refractive correction. The right eye was tested. A standardized dark-adaptation protocol was used that controlled for accommodation and patient alertness. Infrared, still digital photographs were taken after 10 minutes of dark adaptation at 1 lux and were analyzed using digital image software. Testing was performed at baseline in the afternoon, at 3 months in the afternoon, and at 6 months in the morning. Lifestyle factors such as diet and exercise were not controlled.
RESULTS: Mean intersession differences were 0.04 mm (95% confidence interval [CI]: -0.68-0.146), 0.15 mm (95% CI: -0.001-0.297), and 0.09 mm (95% CI: -0.048-0.236) for baseline-3 month, baseline-6 month, and 3 month-6 month comparisons, respectively. None of these differences was significantly different from zero (P>.05, 2-tailed Student t tests). The likelihood that the mean intersession difference was >.25 mm was negligible for all comparisons (P=.9996, .9099, and .9829 respectively, 1-tailed Student t tests).
CONCLUSION: When a consistent dark-adaptation protocol that controls for alertness and accommodation is used, normal young individuals showed no significant variation in the dark-adapted pupil diameter over a 6-month period.