Journal of refractive surgery (Thorofare, N.J. : 1995) · 2001
Effect of hyaluronic acid on corneal haze in a photorefractive keratectomy experimental model.
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Gómez S, Herreras J M, Merayo J, García M, Argüeso P, Cuevas J
Аннотация
PURPOSE: To evaluate the ability of topical hyaluronic acid to decrease corneal opacity after excimer laser photorefractive keratectomy (PRK) in hens.
METHODS: Twenty-four white hens underwent bilateral 193-nm excimer laser PRK to correct -9.00 D of myopia. One eye received postoperative treatment with topical 1% hyaluronic acid six times daily for 3 days; the other eye received phosphate buffered saline. Slit-lamp evaluation by a masked observer was performed for 6 months after PRK, and electron microscopy was carried out at the end of the study.
RESULTS: There were no significant differences in postoperative haze between the eyes treated with hyaluronic acid and those treated with phosphate buffered saline.
CONCLUSION: Topical administration of hyaluronic acid had no effect on the development of corneal haze following PRK in hens.
METHODS: Twenty-four white hens underwent bilateral 193-nm excimer laser PRK to correct -9.00 D of myopia. One eye received postoperative treatment with topical 1% hyaluronic acid six times daily for 3 days; the other eye received phosphate buffered saline. Slit-lamp evaluation by a masked observer was performed for 6 months after PRK, and electron microscopy was carried out at the end of the study.
RESULTS: There were no significant differences in postoperative haze between the eyes treated with hyaluronic acid and those treated with phosphate buffered saline.
CONCLUSION: Topical administration of hyaluronic acid had no effect on the development of corneal haze following PRK in hens.