[Study of the interrelationship of glycemia-nonesterified fatty acids in physical activity in diabetics and patients with a normal glucose tolerance test].

Sixty four experiments were carried out in middle aged diabetics with normal and over-normal body weight and in a control group of patients with NGTT with a parallel follow-up of blood sugar and NEFA with an uptake of 50 g glucose per os and the performance of a moderately difficult physical loading (hiking) or complete rest in a bed for 2.5 hours. A better glucose utilization was found after physical loading in both groups of patients as compared with the rest period. Glucose utilization in patients with diabetes mellitus in physical loading is the same independently of the blood sugar initial level, providing grounds to admit that the betacyte formation apparatus is not strained. NEFA decrease by the 60th minute in diabetics, both in physical loading and at rest does not substantially differ from the subject with NGTT. That comes to show that NEFA utilization in that period is almost the same for the two groups. In patients with NGTT at the end of the physicalloading NEFA is sharply elevated over the initial level (lipolysis), while in diabetics, they remained at the level of the 60th minute.