Journal of pharmacy & bioallied sciences · 2023
Comparative Evaluation of Pimecrolimus Cream 1% and Triamcinolone Aceonide Paste in Treatment of Atrophic-Erosive Oral Lichen Planus.
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Bajoria Atul Anand, Chinnannavar Sangamesh Ningappa, Mishra Silpiranjan, Singh Dhirendra K, Pathi Jugajyoti, Jha Vikash K
Аннотация
OBJECTIVES: This study was done to assess the effects of pimecrolimus cream 1% and triamcinolone aceonide paste in the treatment of atrophic-erosive oral lichen planus.
MATERIALS AND METHODS: A total of 100 patients diagnosed both clinically and histopathologically as lichen planus were considered in the present study. Subjects were classified into two groups. Group I: Patients in this group were treated with 1% pimecrolimus cream and Group II: Patients falling under this group were treated with triamcinolone acetonide in 0.1% concentration.
RESULTS: None of the patients reported worsening clinical signs and symptoms. No significant difference in efficacy and reduction in burning sensation of either pimecrolimus or trimcinolone acetonide was present.
CONCLUSION: Present study found no significant difference in the efficacy of both the agents studied.
MATERIALS AND METHODS: A total of 100 patients diagnosed both clinically and histopathologically as lichen planus were considered in the present study. Subjects were classified into two groups. Group I: Patients in this group were treated with 1% pimecrolimus cream and Group II: Patients falling under this group were treated with triamcinolone acetonide in 0.1% concentration.
RESULTS: None of the patients reported worsening clinical signs and symptoms. No significant difference in efficacy and reduction in burning sensation of either pimecrolimus or trimcinolone acetonide was present.
CONCLUSION: Present study found no significant difference in the efficacy of both the agents studied.